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PMID: 7387621 Published · ppublish English Comparative Study Journal Article

Genetic analysis of protein variations in Mus musculus using two-dimensional electrophoresis.

Biochemical genetics ·Vol. 18 ·No. 1-2 ·1980-02-00 ·Pages 185-97

Racine RR, Langley CH

Abstract

We have investigated the variation of proteins from crude homogenates of mouse kidneys in several strains of Mus musculus by means of two-dimensional electrophoresis. In this study, we have used the strains C57BL/6J, DBA/2J, CD-1, M. m. castaneus, and M. m. molossinus, as well as offspring from crosses among these strains. Out of the 100 loci screened, we have found nine loci showing interstrain differences. We have found also that differences in the protein pattern as seen on two-dimensional gels are small among subspecies of Mus musculus.

MeSH Terms
Animals Crosses, Genetic Electrophoresis, Polyacrylamide Gel Genetic Variation Isoelectric Focusing Kidney/metabolism Mice/genetics Mice, Inbred C57BL/genetics Mice, Inbred DBA/genetics Proteins/genetics
Chemicals
Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Racine R R
Langley C H
References (20)
20 references, click to expand
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Article Info
Journal
Biochemical genetics
Abbr.
Biochem Genet
ISSN
0006-2928
DOI
10.1007/BF00504368
Published
1980-02-00
Pages
185-97
Language
English
Region
United States
NLM ID
0126611
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00504368 View journal details
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