Lipopolysaccharides of R mutants isolated from Vibria cholerae.

The Biochemical journal ·Vol. 185 ·No. 1 ·1980-01-01 ·Pages 77-81

Hisatsune K, Kondo S

Abstract

The chemical and serological properties of lipopolysaccharides isolated from the S form and from the R form of cholera vibrios were compared. It was found that the S-R mutation of cholera vibrios involves total elimination of the two component amino sugars of S-form lipopolysaccharides, i.e. quinovosamine and perosamine. This elimination resulted in the loss of O-specificity of S-form lipopolysaccharides and concomitant appearance of strong serological cross-reactivity, in the passive-haemolysis-inhibition test, among R-form lipopolysaccharides regardless of the serotypes (Inaba and Ogawa) of their S parent strains.

MeSH Terms

Amino Sugars/analysis Antigens, Bacterial Carbohydrates/analysis Cross Reactions Lipopolysaccharides/isolation & purification Mutation Vibrio cholerae/analysis,genetics,immunology

Chemicals

Amino Sugars Antigens, Bacterial Carbohydrates Lipopolysaccharides

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Hisatsune K

Kondo S

References (15)

15 references, click to expand

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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1850077

Published

1980-01-01

Pages

77-81

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1161271

Subset

External Links

PubMed source DOI: 10.1042/bj1850077 PMC Full Text View journal details

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Lipopolysaccharides of R mutants isolated from Vibria cholerae.

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