Cimetidine premedication in elective caesarean section.

Canadian Anaesthetists' Society journal ·Vol. 27 ·No. 1 ·1980-01-00 ·Pages 33-5

Pickering BG, Palahniuk RJ, Cumming M

Abstract

A single intramuscular injection of Cimetidine was compared to oral antacid premedication in 17 patients undergoing elective Caesarean section. Seven patients in the Cimetidine group and four in the antacid group had gastric volumes in excess of 50 ml after induction of anaesthesia, while two patients in each group had gastric pH less than 2.5 after induction. Cimetidine was as effective as antacid in raising gastric pH but neither was completely reliable. This study reconfirms the high gastric volumes in pregnant patients with the need for preventative measures against aspiration during the induction of anaesthesia.

MeSH Terms

Adolescent Adult Anesthesia, General/adverse effects Antacids/therapeutic use Cesarean Section Cimetidine/therapeutic use Female Gastric Juice/metabolism Guanidines/therapeutic use Humans Hydrogen-Ion Concentration Pneumonia, Aspiration/etiology,prevention & control Pregnancy

Chemicals

Antacids Guanidines Cimetidine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Pickering B G

Palahniuk R J

Cumming M

References (9)

9 references, click to expand

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Mendelson's Syndrome.
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Gastric fluid pH in patients receiving cimetidine.
Anesth Analg. 1978 Nov-Dec;57(6):675-7 PMID: 569992
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Article Info

Journal

Canadian Anaesthetists' Society journal

Abbr.

Can Anaesth Soc J

ISSN

0008-2856

DOI

10.1007/BF03006845

Published

1980-01-00

Pages

33-5

Language

English

Region

Canada

NLM ID

0371163

Subset

External Links

PubMed source DOI: 10.1007/BF03006845

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Cimetidine premedication in elective caesarean section.

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