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PMID: 7306060 Published · ppublish English Journal Article

Evolution of the Hong Kong influenza A sub-type. Structural relationships between the haemagglutinin from A/duck/Ukraine/1/63 (Hav 7) and the Hong Kong (H3) haemagglutinins.

The Biochemical journal ·Vol. 195 ·No. 1 ·1981-04-01 ·Pages 337-40

Ward CW, Dopheide TA

Abstract

The relationship between the haemagglutinin from the influenza virus A/duck/Ukraine/1/63 (Hav 7) and the human Hong Kong variants (H3) has been investigated. Amino-acid-sequence analysis shows that the Hav 7 haemagglutinin closely resembles the 1968 human H3 haemagglutinin in structure. However, the number of amino-acid-sequence differences (23) suggest that the Hong Kong haemagglutinin gene did not come directly from A/duck/Ukraine/1/63 but from a virus derived from it by antigenic drift during the period 1963-1968.

MeSH Terms
Amino Acid Sequence Gene Frequency Hemagglutinins, Viral/genetics Influenza A virus/analysis,genetics Oligosaccharides/analysis
Chemicals
Hemagglutinins, Viral Oligosaccharides
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ward C W
Dopheide T A
References (16)
16 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
Published
1981-04-01
Pages
337-40
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1162891
Subset
IM
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