15/15 translocation in Prader-Willi syndrome.

Journal of medical genetics ·Vol. 14 ·No. 4 ·1977-08-00 ·Pages 275-6

Fraccaro M, Zuffardi O, Buhler EM, Jurik LP

Abstract

Two further cases (one previously published as D/D translocation) of 15/15 translocation in Prader-Willi syndrome are reported, which brings the total cases of this specific chromosomal anomaly in connection with this specific syndrome up to three or possibly four. It is suggested that Prader-Willi syndrome might be caused by loss of short arm material of chromosome 15.

MeSH Terms

Child Chromosome Aberrations Chromosome Disorders Chromosomes, Human/ultrastructure Chromosomes, Human, 13-15 Cytological Techniques Genetic Techniques Humans Male Prader-Willi Syndrome/genetics Quinacrine Staining and Labeling Translocation, Genetic

Chemicals

Quinacrine

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Fraccaro M

Zuffardi O

Buhler E M

Jurik L P

References (4)

4 references, click to expand

[Chromosomal translocation in a mentally deficient child with cryptorchidism].
Acta Paediatr. 1963 Mar;52:177-82 PMID: 14041555
Quinacrine fluorescence patterns in somatic chromosomes of a t(15q15q) carrier.
Humangenetik. 1972;15(1):66-70 PMID: 5046909
Translocation between both members of chromosome pair number 15 causing recurrent abortions.
Ann Hum Genet. 1969 May;32(4):347-52 PMID: 5822322
The Prader-Willi syndrome with a 15/15 translocation. Case report and review of the literature.
J Med Genet. 1976 Apr;13(2):152-7 PMID: 933113

Article Info

Journal

Journal of medical genetics

Abbr.

J Med Genet

ISSN

0022-2593

DOI

10.1136/jmg.14.4.275

Published

1977-08-00

Pages

275-6

Language

English

Region

England

NLM ID

2985087R

PMCID

PMC1013583

Subset

External Links

PubMed source DOI: 10.1136/jmg.14.4.275 PMC Full Text View journal details

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15/15 translocation in Prader-Willi syndrome.

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