Sodium-dependent alanine transport in plasma-membrane vesicles from rat liver.

The Biochemical journal ·Vol. 174 ·No. 3 ·1978-09-15 ·Pages 1083-6

van Amelsvoort JM, Sips HJ, van Dam K

Abstract

L-Alanine transport was studied in plasma-membrane vesicles from rat liver. A gradient of NaSCN, but not of KSCN, stimulated alanine uptake. Monensin plus carbonyl cyanide p-trifluoromethoxyphenylhydrazone abolished the observed overshoot in uptake. After equilibration of alanine, NaSCN induced uphill transport.

MeSH Terms

Alanine/metabolism Animals Biological Transport/drug effects Cell Membrane/metabolism In Vitro Techniques Liver/drug effects,metabolism Male Potassium/pharmacology RNA/metabolism Rats Sodium/pharmacology

Chemicals

RNA Sodium Alanine Potassium

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

van Amelsvoort J M

Sips H J

van Dam K

References (18)

18 references, click to expand

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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1741083

Published

1978-09-15

Pages

1083-6

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1186018

Subset

External Links

PubMed source DOI: 10.1042/bj1741083 PMC Full Text View journal details

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Sodium-dependent alanine transport in plasma-membrane vesicles from rat liver.

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