Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

Animals Azides/pharmacology Biological Transport/drug effects Cell Line Cell Survival/drug effects Chlorocebus aethiops Deoxyglucose/pharmacology Diphtheria Toxin/isolation & purification,metabolism,pharmacology HeLa Cells/drug effects,metabolism Humans Hydrogen-Ion Concentration Kidney Kinetics Protein Biosynthesis/drug effects

Azides Diphtheria Toxin Deoxyglucose