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PMID: 7251167 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Specificities of albumin receptors and albumin antibodies.

Infection and immunity ·Vol. 32 ·No. 3 ·1981-06-00 ·Pages 1292-4

Thung SN, Gerber MA

Abstract

Receptor sites for polymerized human serum albumin (pHSA) on the envelope of hepatitis B virus (hepatitis B surface antigen) and antibodies to pHSA in sera of patients with liver disease were differentiated by an indirect fluorescent antibody method. Analysis of the specificities of pHSA receptors and antibodies to pHSA by hemagglutination inhibition suggested that pHSA receptors reacted with a species-specific site on pHSA, whereas "autoantibodies" to pHSA cross-reacted with pHSA from different species. These human antibodies inhibited the binding of hepatitis B surface antigen-associated receptors to pHSA.

MeSH Terms

Antibody Specificity Autoantibodies Hepatitis B Surface Antigens/immunology Hepatitis B virus Humans Liver/microbiology Liver Diseases/immunology Receptors, Immunologic Receptors, Virus Serum Albumin/immunology

Chemicals

Autoantibodies Hepatitis B Surface Antigens Receptors, Immunologic Receptors, Virus Serum Albumin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Thung S N

Gerber M A

References (14)

14 references, click to expand

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Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.32.3.1292-1294.1981

Published

1981-06-00

Pages

1292-4

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC351591

Subset

Grants

NIAID NIH HHS · AI00035 · United States

External Links

PubMed source DOI: 10.1128/iai.32.3.1292-1294.1981 PMC Full Text View journal details

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