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PMID: 7251050 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Antigen-induced non-specific suppressor factor in sheep efferent lymph is prostaglandin E2.

Immunology ·Vol. 43 ·No. 1 ·1981-05-00 ·Pages 205-12

Hopkins J, McConnell I, Raniwalla J

Abstract

Efferent lymph from the popliteal node of sheep challenged with antigen was found to suppress the in vitro transformation of sheep peripheral blood lymphocytes to a variety of antigens. The suppressor factor appeared 6-20 hr after challenged of the node and was shown to be prostaglandin E2, probably complexed to albumin.

MeSH Terms
Animals Antigens/immunology Chemical Fractionation Chromatography, Affinity Immunosuppression Therapy Lymph/analysis,immunology Lymphocyte Activation Prostaglandins E/analysis,immunology Sheep Tuberculin/immunology
Chemicals
Antigens Prostaglandins E Tuberculin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hopkins J
McConnell I
Raniwalla J
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29 references, click to expand
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Article Info
Journal
Immunology
Abbr.
Immunology
ISSN
0019-2805
Published
1981-05-00
Pages
205-12
Language
English
Region
England
NLM ID
0374672
PMCID
PMC1555188
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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