Home LiteratureArticle Details
PMID: 7242700 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Inhibition of synaptosomal choline uptake by tetanus and botulinum A toxin. Partial dissociation of fixation and effect of tetanus toxin.

Naunyn-Schmiedeberg's archives of pharmacology ·Vol. 316 ·No. 2 ·1981-04-00 ·Pages 135-42

Habermann E, Bigalke H, Heller I

Abstract

暂无摘要

MeSH Terms
Animals Botulinum Toxins/pharmacology Choline/metabolism Dose-Response Relationship, Drug In Vitro Techniques Neuraminidase/pharmacology Rats Synaptosomes/drug effects,metabolism Tetanus Antitoxin/pharmacology Tetanus Toxin/metabolism,pharmacology Time Factors
Chemicals
Tetanus Antitoxin Tetanus Toxin Neuraminidase Botulinum Toxins Choline
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Habermann E
Bigalke H
Heller I
References (26)
26 references, click to expand
  1. Inhibition by botulinum toxin of depolarization-evoked release of (14C)acetylcholine from synaptosomes in vitro.
    Biochem J. 1976 Jun 15;156(3):701-12 PMID: 949350
  2. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples.
    Anal Biochem. 1978 Jun 15;87(1):206-10 PMID: 98070
  3. The effects of botulinum toxin on acetylcholine metabolism in mouse brain slices and synaptosomes.
    J Neurochem. 1978 Oct;31(4):1005-13 PMID: 702132
  4. The neurotoxins of Clostridium botulinum and Clostridium tetani.
    Pharmacol Rev. 1955 Dec;7(4):413-65 PMID: 13289310
  5. Affinity chromatography purification of type A botulinum neurotoxin from crystalline toxic complex.
    Appl Environ Microbiol. 1978 May;35(5):878-80 PMID: 655704
  6. Relationship of choline uptake to acetylcholine synthesis and release.
    Prog Brain Res. 1979;49:77-88 PMID: 390614
  7. Effect of cooling, local anaesthetic compounds and botulinum toxin on the responses of and the acetylcholine output from the electrically transmurally stimulated isolated guinea-pig ileum.
    Br J Pharmacol Chemother. 1962 Aug;19:42-55 PMID: 13904922
  8. Tetanus toxin and botulinum A toxin inhibit acetylcholine release from but not calcium uptake into brain tissue.
    Naunyn Schmiedebergs Arch Pharmacol. 1981 Apr;316(2):143-8 PMID: 7242701
  9. Kinetic studies on the interaction between botulinum toxin type A and the cholinergic neuromuscular junction.
    J Pharmacol Exp Ther. 1980 Jan;212(1):16-21 PMID: 6243359
  10. Effect of botulinum toxin on autonomic nerves in a dually innervated tissue.
    Nature. 1967 Jan 28;213(5074):394-5 PMID: 5339739
  11. Tetanus toxin blocks the neuromuscular transmission in vitro like botulinum A toxin.
    Naunyn Schmiedebergs Arch Pharmacol. 1980 Feb;311(1):33-40 PMID: 6245375
  12. The action of botulinum toxin on the neuro-muscular junction.
    J Physiol. 1949 Aug;109(1-2):10-24 PMID: 15394302
  13. On the similarity of tetanus and cholera toxins.
    Naunyn Schmiedebergs Arch Pharmacol. 1973;276(3-4):289-95 PMID: 4268160
  14. Direct evidence for the specific fixation of Cl. botulinum A neurotoxin to brain matter.
    Naunyn Schmiedebergs Arch Pharmacol. 1975;287(1):97-106 PMID: 1118043
  15. Inhibition by botulinum toxin of acetylcholine release from synaptosomes: latency of action and the role of gangliosides.
    J Neurochem. 1980 Jun;34(6):1567-73 PMID: 7381483
  16. Blockade by tetanus and botulinum A toxin of postganglionic cholinergic nerve endings in the myenteric plexus.
    Naunyn Schmiedebergs Arch Pharmacol. 1980 Jul;312(3):255-63 PMID: 7402367
  17. Effect of tetanus toxin on transmitter release from substantia nigra and striatum in vitro.
    J Neurochem. 1980 Mar;34(3):540-7 PMID: 7354328
  18. Pharmacokinetic and histoautoradiographic evidence for the intraaxonal movement of toxin in the pathogenesis of tetanus.
    Toxicon. 1978;16(6):611-23 PMID: 83031
  19. The mechanism of action of tetanus toxin: effect on synaptic processes and some particular features of toxin binding by the nervous tissue.
    Naunyn Schmiedebergs Arch Pharmacol. 1973;276(3-4):247-70 PMID: 4351283
  20. Metabolic fate of 125I-tetanus toxin in the spinal cord of rats and cats with early local tetanus.
    Naunyn Schmiedebergs Arch Pharmacol. 1977 Sep;299(2):187-96 PMID: 409958
  21. Effects of Cl. botulinum type A toxin on the isolated cat heart.
    Arch Int Pharmacodyn Ther. 1966 Feb;159(2):281-7 PMID: 5331045
  22. Kinetics of [3H]acetylcholine synthesis and release in primary cell cultures from mammalian CNS.
    J Neurochem. 1978 Apr;30(4):871-9 PMID: 650227
  23. Tetanus toxin.
    Microbiol Rev. 1979 Jun;43(2):224-40 PMID: 390355
  24. Suppression of 3H-acetylcholine release from primary nerve cell cultures by tetanus and botulinum-A toxin.
    Naunyn Schmiedebergs Arch Pharmacol. 1978 Jun;303(2):133-8 PMID: 673020
  25. Choline transport is not coupled to acetylcholine synthesis.
    Nature. 1979 Jun 7;279(5713):542-4 PMID: 450100
  26. Tetanus toxin and thyrotropin interactions with rat brain membrane preparations.
    J Biol Chem. 1979 May 25;254(10):3826-32 PMID: 220221
Article Info
Journal
Naunyn-Schmiedeberg's archives of pharmacology
Abbr.
Naunyn Schmiedebergs Arch Pharmacol
ISSN
0028-1298
Published
1981-04-00
Pages
135-42
Language
English
Region
Germany
NLM ID
0326264
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com