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PMID: 7229026 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Foetal myosin light chain in human ventricle.

Journal of muscle research and cell motility ·Vol. 1 ·No. 3 ·1980-09-00 ·Pages 357-66

Cummins P, Price KM, Littler WA

Abstract

Myosin light chain subunits from adult human atria and ventricle were characterized by two-dimensional gel electrophoresis. Atrial (ALC-1 and ALC-2) differed from ventricular (VLC-1 and VLC-2) light chains. Foetal (18--21 week) ventricle contained VLC-1 plus a foetal light chain (FLC-1) which could not be distinguished from adult ALC-1. Myosin FLC-1 was gradually lost from the ventricle and replaced by VLC-1 during foetal development and in the immediate postnatal period.

MeSH Terms
Age Factors Heart Atria/analysis,embryology Heart Ventricles/analysis,embryology Humans Isoelectric Point Isoenzymes/analysis Molecular Weight Myosins/analysis
Chemicals
Isoenzymes Myosins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Cummins P
Price K M
Littler W A
References (22)
22 references, click to expand
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Article Info
Journal
Journal of muscle research and cell motility
Abbr.
J Muscle Res Cell Motil
ISSN
0142-4319
DOI
10.1007/BF00711936
Published
1980-09-00
Pages
357-66
Language
English
Region
Netherlands
NLM ID
8006298
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00711936 View journal details
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