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PMID: 7216432 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Heterotypic immunity to influenza in ferrets.

Infection and immunity ·Vol. 29 ·No. 2 ·1980-08-00 ·Pages 650-3

Yetter RA, Barber WH, Small PA

Abstract

Heterotypic immunity to influenza virus in ferrets operated against heterotypic influenza viruses but not heterologous viruses. Contrary to prior reports, the protection conferred lasted for at least 18 months. This type of immunity limited virus shedding but did not prevent infection. These results suggest that this phenomenon could play a role in determining the severity of infections caused by type A influenza viruses in humans.

MeSH Terms

Age Factors Animals Ferrets Hemagglutination Inhibition Tests Male Orthomyxoviridae/immunology Orthomyxoviridae Infections/immunology,microbiology Recurrence Species Specificity Time Factors

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Yetter R A

Barber W H

Small P A

References (7)

7 references, click to expand

Studies with avian influenza A viruses: cross protection experiments in chickens.
J Gen Virol. 1971 Aug;12(2):79-84 PMID: 5123326
Dissemination of influenza virus between anatomically isolated sites in ferrets.
Infect Immun. 1974 Mar;9(3):530-3 PMID: 4816632
Immunity to influenza in ferrets. VII. Effect of previous infection with heterotypic and heterologous influenza viruses on the response of ferrets to inactivated influenza virus vaccines.
J Hyg (Lond). 1974 Feb;72(1):91-100 PMID: 4522247
Influenza infection in ferrets: role of serum antibody in protection and recovery.
Infect Immun. 1976 Feb;13(2):417-24 PMID: 1262059
Outcome of influenza infection: effect of site of initial infection and heterotypic immunity.
Infect Immun. 1980 Aug;29(2):654-62 PMID: 7216433
Application of a microtechnique to viral serological investigations.
J Immunol. 1962 Mar;88:320-9 PMID: 13910995
INDUCTION OF PARTIAL SPECIFIC HETEROTYPIC IMMUNITY IN MICE BY A SINGLE INFECTION WITH INFLUENZA A VIRUS.
J Bacteriol. 1965 Jan;89:170-4 PMID: 14255658

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.29.2.650-653.1980

Published

1980-08-00

Pages

650-3

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC551176

Subset

Grants

NIAID NIH HHS · AI 0128 · United States

NIAID NIH HHS · AI 07713 · United States

External Links

PubMed source DOI: 10.1128/iai.29.2.650-653.1980 PMC Full Text View journal details

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Heterotypic immunity to influenza in ferrets.

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