Isolation and properties of a temperature-sensitive mutant (ts 412) of an influenza A virus recombinant with a ts lesion in the gene coding for the nonstructural protein.

Animals Cells, Cultured Chick Embryo DNA-Directed RNA Polymerases/metabolism Genes, Viral Hemagglutinins, Viral/biosynthesis Influenza A virus/classification,genetics,isolation & purification Microscopy, Electron Mutation Neuraminidase/biosynthesis RNA, Viral/genetics Recombination, Genetic Temperature Viral Proteins/genetics,metabolism Virus Replication

Hemagglutinins, Viral RNA, Viral Viral Proteins DNA-Directed RNA Polymerases Neuraminidase