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PMID: 7191869 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Establishment and characterization of a murine hybridoma secreting monoclonal anti-DNA autoantibody.

Journal of immunology (Baltimore, Md. : 1950) ·Vol. 125 ·No. 6 ·1980-12-00 ·Pages 2805-9

Tron F, Charron D, Bach JF, Talal N

Abstract

Twenty-five clones of hybridoma cells secreting anti-DNA autoantibodies were isolated after fusions between plasmacytoma cells (P3-x 63 Ag 8.653) and spleen cells from nonimmunized autoimmune NZB/NZW F1 (B/W) mice. A monoclonal anti-DNA autoantibody was immunochemically analyzed.

MeSH Terms

Animals Antibody-Producing Cells/immunology Autoantibodies Autoradiography Cattle Cell Fusion Cell Line Clone Cells/immunology DNA/immunology Female Hybrid Cells/immunology,metabolism Mice Mice, Inbred BALB C Pregnancy

Chemicals

Autoantibodies DNA

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Tron F

Charron D

Bach J F

Talal N

Article Info

Journal

Journal of immunology (Baltimore, Md. : 1950)

Abbr.

J Immunol

ISSN

0022-1767

Published

1980-12-00

Pages

2805-9

Language

English

Region

United States

NLM ID

2985117R

Subset

Grants

NIADDK NIH HHS · AM-16140 · United States

NIADDK NIH HHS · AM-25310 · United States

External Links

PubMed source View journal details

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Establishment and characterization of a murine hybridoma secreting monoclonal anti-DNA autoantibody.

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