Serum antibody response to Clostridium botulinum toxin in infant botulism.

Journal of clinical microbiology ·Vol. 16 ·No. 4 ·1982-10-00 ·Pages 770-1

Rubin LG, Dezfulian M, Yolken RH

Abstract

A serum antibody response has not been previously demonstrated after infection with Clostridium botulinum. We developed an enzyme immunoassay for measuring serum antibody to C. botulinum toxins A, B, and E. This assay system detected a specific immunoglobulin G and immunoglobulin M antibody response to C. botulinum toxin in two patients with infant botulism.

MeSH Terms

Antibody Formation Botulinum Toxins/immunology Botulism/immunology Female Humans Immunoglobulin M/analysis Infant

Chemicals

Immunoglobulin M Botulinum Toxins

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Rubin L G

Dezfulian M

Yolken R H

References (4)

4 references, click to expand

Syndrome of botulism in infancy: clinical and electrophysiologic study.
N Engl J Med. 1976 Sep 30;295(14):770-2 PMID: 785257
Infant botulism. Epidemiological, clinical, and laboratory aspects.
JAMA. 1977 May 2;237(18):1946-51 PMID: 321825
Laboratory procedures for cases of suspected infant botulism.
Rev Infect Dis. 1979 Jul-Aug;1(4):647-51 PMID: 551514
Quantitation of Clostridium botulinum organisms and toxin in the feces of an infant with botulism.
J Clin Microbiol. 1982 Jan;15(1):1-4 PMID: 6764763

Article Info

Journal

Journal of clinical microbiology

Abbr.

J Clin Microbiol

ISSN

0095-1137

DOI

10.1128/jcm.16.4.770-771.1982

Published

1982-10-00

Pages

770-1

Language

English

Region

United States

NLM ID

7505564

PMCID

PMC272469

Subset

External Links

PubMed source DOI: 10.1128/jcm.16.4.770-771.1982 PMC Full Text View journal details

Analysis Services

Serum antibody response to Clostridium botulinum toxin in infant botulism.

Contact

WeChat Official Account