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PMID: 7109029 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Fatty acid modification of Newcastle disease virus glycoproteins.

Journal of virology ·Vol. 43 ·No. 1 ·1982-07-00 ·Pages 342-7

Chatis PA, Morrison TG

Abstract

The fatty acid acylation of Newcastle disease virus hemagglutininin-neuraminidase and fusion glycoproteins was assayed. [3H]palmitate label was associated with cytoplasmic fusion proteins (F0 and F1) and virion-associated F1. In contrast, there was no detectable [3H]palmitate label associated with the hemagglutin-neuraminidase protein in Newcastle disease virus-infected Chinese hamster ovary cells or chicken embryo cells or in virions released from these cells. Thus, fatty acid modification may not be important for the maturation of some glycoproteins.

MeSH Terms
Acylation Animals Cell Line Chick Embryo Cricetinae Female Glycoproteins/metabolism Hemagglutinins, Viral Neuraminidase Newcastle disease virus/metabolism Palmitic Acid Palmitic Acids/metabolism Viral Proteins/metabolism
Chemicals
Glycoproteins Hemagglutinins, Viral Palmitic Acids Viral Proteins Palmitic Acid Neuraminidase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Chatis P A
Morrison T G
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.43.1.342-347.1982
Published
1982-07-00
Pages
342-7
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC256127
Subset
IM
Grants
NIAID NIH HHS · NIH R01 AI-13847 · United States
External Links
PubMed source DOI: 10.1128/JVI.43.1.342-347.1982 PMC Full Text View journal details
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