In vitro activity of thienamycin.

Antimicrobial agents and chemotherapy ·Vol. 14 ·No. 3 ·1978-09-00 ·Pages 436-8

Tally FP, Jacobus NV, Gorbach SL

Abstract

The in vitro activity of thienamycin was tested against 135 aerobic and anaerobic bacteria. The compound was highly active against resistant gram-negative bacilli and penicillin-resistant Straphylococcus aureus. The antianaerobic spectrum of the drug seemed to be comparable to that of metronidazole.

MeSH Terms

Anti-Bacterial Agents/pharmacology Bacteria/drug effects Lactams/pharmacology Thienamycins

Chemicals

Anti-Bacterial Agents Lactams Thienamycins thienamycin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Tally F P

Jacobus N V

Gorbach S L

References (6)

6 references, click to expand

Binding of thienamycin and clavulanic acid to the penicillin-binding proteins of Escherichia coli K-12.
Antimicrob Agents Chemother. 1977 Sep;12(3):406-9 PMID: 334066
Therapy for infections due to anaerobic bacteria: an overview.
J Infect Dis. 1977 Mar;135 Suppl:S25-9 PMID: 321708
Susceptibility of anaerobic bacteria to 23 antimicrobial agents.
Antimicrob Agents Chemother. 1976 Oct;10(4):736-52 PMID: 984809
Activity of cefamandole and other cephalosporins against aerobic and anaerobic bacteria.
Antimicrob Agents Chemother. 1976 May;9(5):852-5 PMID: 949182
Bacteroides fragilis resistant to the administration of clindamycin.
Am J Med. 1976 Mar;60(3):426-8 PMID: 1258888
Susceptibility of anaerobes to cefoxitin and other cephalosporins.
Antimicrob Agents Chemother. 1975 Feb;7(2):128-32 PMID: 1137364

Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.14.3.436

Published

1978-09-00

Pages

436-8

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC352476

Subset

External Links

PubMed source DOI: 10.1128/AAC.14.3.436 PMC Full Text View journal details

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In vitro activity of thienamycin.

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