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PMID: 7071599 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Sodium transport inhibition by amiloride reduces basolateral membrane potassium conductance in tight epithelia.

Science (New York, N.Y.) ·Vol. 216 ·No. 4545 ·1982-04-30 ·Pages 525-7

Davis CW, Finn AL

Abstract

In toad and frog urinary bladder, electrophysiological data suggest that inhibition of transepithelial sodium transport by mucosal amiloride results in a decrease in basolateral membrane conductance. These results were confirmed by showing that amiloride addition caused a decrease in basolateral membrane potassium permeability.

MeSH Terms

Amiloride/pharmacology Animals Anura Biological Transport, Active/drug effects Epithelium/drug effects Membrane Potentials/drug effects Potassium/physiology Pyrazines/pharmacology Sodium/physiology Urinary Bladder

Chemicals

Pyrazines Amiloride Sodium Potassium

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Davis C W

Finn A L

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.7071599

Published

1982-04-30

Pages

525-7

Language

English

Region

United States

NLM ID

0404511

Subset

Grants

NIADDK NIH HHS · AM17854 · United States

NIADDK NIH HHS · AM25483 · United States

External Links

PubMed source DOI: 10.1126/science.7071599 View journal details

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Sodium transport inhibition by amiloride reduces basolateral membrane potassium conductance in tight epithelia.

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