Klinefelter's syndrome and acute non-lymphocytic leukemia.

Blut ·Vol. 44 ·No. 1 ·1982-01-00 ·Pages 15-20

Muts-Homsma SJ, Muller HP, Geraedst JP

Abstract

In five out of 51 adult, male patients with acute non-lymphocytic leukemia, Klinefelter's syndrome was demonstrated karyotypically. The incidence of this syndrome in our material is very much increased in comparison with the frequency at birth. In this article the medical histories of the patients are given and the possible connection between the constitutional chromosome abnormality and acute non-lymphocytic leukemia is discussed. Immunological or hormonal abnormalities or an increased virus susceptibility might be predisposing factors.

MeSH Terms

Acute Disease Adult Blood Cells/pathology Bone Marrow/pathology Humans Karyotyping Klinefelter Syndrome/complications Leukemia/complications Male Middle Aged

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Muts-Homsma S J

Muller H P

Geraedst J P

References (19)

19 references, click to expand

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Article Info

Journal

Blut

Abbr.

Blut

ISSN

0006-5242

DOI

10.1007/BF00320682

Published

1982-01-00

Pages

15-20

Language

English

Region

Germany

NLM ID

0173401

Subset

External Links

PubMed source DOI: 10.1007/BF00320682

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Klinefelter's syndrome and acute non-lymphocytic leukemia.

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