On the role of the Escherichia coli RNA polymerase sigma factor in T4 phage development.

Molecular & general genetics : MGG ·Vol. 183 ·No. 3 ·1981-00-00 ·Pages 557-8

Zograff YN

Abstract

The rpoD800 mutation causing the temperature sensitivity of Escherichia coli RNA polymerase sigma factor has been used to demonstrate that the bacterial sigma factor is necessary throughout T4 phage development. In T4-infected RpoD800 mutant cells RNA synthesis is equally depressed at restrictive temperature at early and late stages of infection. The results show the bacterial sigma factor to be necessary for the synthesis of all RNA types in infected cells.

MeSH Terms

DNA, Viral/metabolism DNA-Directed RNA Polymerases/genetics Escherichia coli/genetics Mutation RNA, Viral/metabolism Sigma Factor/genetics T-Phages/growth & development Transcription Factors/genetics

Chemicals

DNA, Viral RNA, Viral Sigma Factor Transcription Factors DNA-Directed RNA Polymerases

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Zograff Y N

References (15)

15 references, click to expand

Differential amplification of specific areas of phage T4 genome as revealed by hybridization to cloned genetic segments.
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5064-8 PMID: 7001470
Breaks in DNA stimulate transcription by core RNA polymerase.
Nature. 1969 Aug 23;223(5208):854-5 PMID: 4894964
Novel RNA polymerase sigma factor from Bacillus subtilis.
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7000-4 PMID: 6784117
The interaction bacterial and phage proteins with immobilized Escherichia coli RNA polymerase.
J Mol Biol. 1974 Sep 15;88(2):373-83 PMID: 4616088
Host mutant (tabD)-induced inhibition of bacteriophage T4 late transcription. I. Isolation and phenotypic characterization of the mutants.
J Mol Biol. 1975 Aug 25;96(4):579-600 PMID: 1195367
A new mutation rpoD800, affecting the sigma subunit of E. coli RNA polymerase is allelic to two other sigma mutants.
Mol Gen Genet. 1980 Jan;177(2):277-82 PMID: 6988671
Distinctive nucleotide sequences of promoters recognized by RNA polymerase containing a phage-coded "sigma-like" protein.
Proc Natl Acad Sci U S A. 1979 Nov;76(11):5465-9 PMID: 118447
Transcription termination factor rho and T-even phage development.
Mol Gen Genet. 1980;177(4):699-705 PMID: 6991874
Promoter recognition by phage SP01-modified RNA polymerase.
Proc Natl Acad Sci U S A. 1978 Mar;75(3):1185-9 PMID: 418406
A modified RNA polymerase transcribes a cloned gene under sporulation control in Bacillus subtilis.
Nature. 1979 Nov 15;282(5736):256-60 PMID: 116131
A sporulation-induced sigma-like regulatory protein from B. subtilis.
Cell. 1981 Feb;23(2):615-24 PMID: 6781761
New small polypeptides associated with DNA-dependent RNA polymerase of Escherichia coli after infection with bacteriophage T4.
Proc Natl Acad Sci U S A. 1972 Mar;69(3):603-7 PMID: 4551978
The role of replication proteins in the regulation of bacteriophage T4 transcription. II. Gene 45 and late transcription uncoupled from replication.
J Mol Biol. 1975 Aug 25;96(4):539-62 PMID: 1195366
Transcription during bacteriophage T4 development: requirements for late messenger synthesis.
J Mol Biol. 1968 Apr 28;33(2):339-62 PMID: 4302631
Rifampicin resistant DNA synthesis in phage T4 infected Escherichia coli.
Biochem Biophys Res Commun. 1973 Dec 10;55(3):993-1000 PMID: 4586624

Article Info

Journal

Molecular & general genetics : MGG

Abbr.

Mol Gen Genet

ISSN

0026-8925

DOI

10.1007/BF00268782

Published

1981-00-00

Pages

557-8

Language

English

Region

Germany

NLM ID

0125036

Subset

External Links

PubMed source DOI: 10.1007/BF00268782

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On the role of the Escherichia coli RNA polymerase sigma factor in T4 phage development.

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