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PMID: 7029212 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The muc+ gene of plasmid pKM101 prevents respiration shutoff in far ultraviolet-irradiated Salmonella typhimurium.

Molecular & general genetics : MGG ·Vol. 182 ·No. 3 ·1981-00-00 ·Pages 422-5

Swenson PA

Abstract

The plasmid PKM101 is known to protect Escherichia coli and Salmonella typhimurium against killing by far UV irradiation and to enhance UV-induced mutagenesis. The muc+ gene of the plasmid is responsible for both of these effects. This paper shows that respiration of S. typhimurium shuts off about an hour after UV irradiation and that pKM101 prevents the shutoff. Plasmids which contained Tn5 translocatable elements, either in (and having produced a muc mutation) or flanking the muc+ gene, have been introduced into S. typhimurium. The muc mutant plasmid, which does not protect its host against UV killing and does not enhance UV induced mutagenesis, also does not protect against UV induced respiration shutoff. Likewise, plasmids in which the Tn5 translocatable elements flank the muc+ gene protect against shutoff of respiration. Thus the muc+ gene of pKM101 is responsible for protection against UV induced shutoff of respiration in S. typhimurium.

MeSH Terms
DNA Repair Genes, Bacterial Oxygen Consumption Plasmids Salmonella typhimurium/genetics,metabolism,radiation effects Ultraviolet Rays
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Swenson P A
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21 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00293930
Published
1981-00-00
Pages
422-5
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00293930
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