| GeneLibs

题目:: Immunopotentiating activity of whole cells and mini-cells of Salmonella typhimurium.
作者:: Kurashige(S),Yoshida(T),Kodama(K),Mitsuhashi(S)
状态:: 发布时间1981-11-22 , 更新时间 2003-11-14
期刊:: Microbiol Immunol
摘要:: Salmonella typhimurium strain 9 produces mini-cells during cell proliferation. Mini-cells are viable but cannot proliferate since they do not contain chromosomal DNA. Effects of whole cells and mini-cells of S. typhimurium on the immune responses were investigated, with the following results. Phagocytosis of peritoneal macrophages was enhanced by in vivo stimulation of both whole cells and mini-cells. Cellular immunity against L1210 cells (mouse leukemia cells) and Sarcoma 180 cells was also enhanced by both whole cells and mini-cells. Mini-cells slightly stimulated in vitro blast cell transformation of normal mouse lymphocytes. Whole cells of S. typhimurium induced antibody-forming cells to produce IgG of higher affinity but mini-cells did not. Mini-cells were not directly cytotoxic for normal lymphocytes or L1210 cells.
语言:: eng
DOI:

文献库文献相关信息