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PMID: 7014556 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Peptide toxins from Conus geographus venom.

The Journal of biological chemistry ·Vol. 256 ·No. 10 ·1981-05-25 ·Pages 4734-40

Gray WR, Luque A, Olivera BM, Barrett J, Cruz LJ

Abstract

Three homologous toxic peptides which cause postsynaptic inhibition at the vertebrate neuromuscular junction have been purified from the venom of the marine snail Conus geographus. Their amino acid sequences are: (formula see text) The biologically active peptides are monomeric, with internal disulfide bonds.

MeSH Terms

Amino Acid Sequence Animals Conotoxins Disulfides/analysis Mollusk Venoms/pharmacology Muscle Contraction/drug effects Peptide Fragments/analysis Peptide Hydrolases Rana pipiens Snails

Chemicals

Conotoxins Disulfides Mollusk Venoms Peptide Fragments conotoxin GI conotoxin GII conotoxin GIA Peptide Hydrolases

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Gray W R

Luque A

Olivera B M

Barrett J

Cruz L J

Article Info

Journal

The Journal of biological chemistry

Abbr.

J Biol Chem

ISSN

0021-9258

Published

1981-05-25

Pages

4734-40

Language

English

Region

United States

NLM ID

2985121R

Subset

Grants

NIGMS NIH HHS · GM-22737 · United States

External Links

PubMed source View journal details

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Peptide toxins from Conus geographus venom.

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