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PMID: 7013092 Published · ppublish English Journal Article

Plasmodium falciparum strains from Papua New Guinea: culture characteristics and drug sensitivity.

The Southeast Asian journal of tropical medicine and public health ·Vol. 11 ·No. 4 ·1980-12-00 ·Pages 435-40

Chen P, Lamont G, Elliott T, Kidson C, Brown G, Mitchell G, Stace J, Alpers M

Abstract

Seven strains of Plasmodium falciparum from Papua New Guinea have been established in continuous in vitro culture. Samples with a high initial parasitaemia were more likely to form continuous lines, possibly due to the time required for transport of infected blood samples from Papua New Guinea to laboratories in Australia. Most but not all established lines were resistant to chloroquine and all were resistant to pyrimethamine, possibly reflecting the parasite strain characteristics in that region.

MeSH Terms
Adolescent Adult Animals Child, Preschool Chloroquine/therapeutic use Humans Malaria/parasitology New Guinea Plasmodium falciparum/drug effects Pyrimethamine/therapeutic use
Chemicals
Chloroquine Pyrimethamine
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Chen P
Lamont G
Elliott T
Kidson C
Brown G
Mitchell G
Stace J
Alpers M
Article Info
Journal
The Southeast Asian journal of tropical medicine and public health
Abbr.
Southeast Asian J Trop Med Public Health
ISSN
0125-1562
Published
1980-12-00
Pages
435-40
Language
English
Region
Thailand
NLM ID
0266303
Subset
IM
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