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PMID: 7007323 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Methyl-accepting chemotaxis protein III and transducer gene trg.

Journal of bacteriology ·Vol. 145 ·No. 1 ·1981-01-00 ·Pages 43-9

Hazelbauer GL, Engström P, Harayama S

Abstract

A comparison of the two-dimensional gel patterns of methyl-3H- and 35S-labeled membrane proteins from trg+ and trg null mutant strains of Escherichia coli indicated that the product of trg is probably methyl-accepting chemotaxis protein III. Like the other known methyl-accepting chemotaxis proteins, the trg product is a membrane protein that migrates as more than one species in sodium dodecyl sulfate-polyacrylamide gel electrophoresis, implying that it too is multiple methylated. It appears likely that all chemoreceptors are linked to the tumble regulator through a single class of membrane protein transducers which are methyl-accepting proteins. Three transducers are coded for by genes tsr, tar, and, probably, trg. Another methyl-accepting protein, which is not related to any of these genes, was observed.

MeSH Terms
Bacterial Proteins/analysis,genetics Chemotactic Factors/analysis,genetics Chemotaxis Escherichia coli/genetics,physiology Genes Membrane Proteins/analysis,genetics Methyl-Accepting Chemotaxis Proteins Methylation Mutation
Chemicals
Bacterial Proteins Chemotactic Factors Membrane Proteins Methyl-Accepting Chemotaxis Proteins tsr protein, E coli
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hazelbauer G L
Engström P
Harayama S
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31 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.145.1.43-49.1981
Published
1981-01-00
Pages
43-9
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC217242
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.145.1.43-49.1981 PMC Full Text View journal details
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