Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes.

Animals Aryl Hydrocarbon Hydroxylases/genetics,physiology Benzopyrenes/metabolism Biotransformation Enzymes/physiology Gene Expression Regulation Humans Inactivation, Metabolic Microsomes/enzymology Mixed Function Oxygenases/physiology Mutation/drug effects Neoplasms/chemically induced,enzymology Oxidoreductases/physiology Protein Binding/drug effects

Benzopyrenes Enzymes Mixed Function Oxygenases Oxidoreductases Aryl Hydrocarbon Hydroxylases