Reduction of the cerebellar stimulus effect on rat Deiters neurons after chemical destruction of the inferior olive.

Experimental brain research ·Vol. 33 ·No. 1 ·1978-09-15 ·Pages 143-5

Ito M, Orlov I, Shimoyama I

Abstract

After the inferior olive of the rats had been destroyed by administration of 3-Acetylpyridine, the inhibitory effect of cerebellar stimulation on Deiters neurons was substantially reduced, indicating impairment in functions of Purkinje cells and/or their axons after deprivation of climbing fiber afferents from the cerebellum.

MeSH Terms

Afferent Pathways/physiology Animals Cerebellum/physiology Electric Stimulation Neural Inhibition Neurons/physiology Olivary Nucleus/drug effects,physiology Purkinje Cells/drug effects,physiology Pyridines/pharmacology Rats Time Factors

Chemicals

Pyridines

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Ito M

Orlov I

Shimoyama I

References (6)

6 references, click to expand

Diminution and reversal of eye movements induced by local stimulation of rabbit cerebellar flocculus after partial destruction of the inferior olive.
Exp Brain Res. 1978 Sep 15;33(1):139-41 PMID: 699997
Cerebella control of the vestibulospinal tract cells in rabbit.
Exp Brain Res. 1973 Dec 20;18(5):446-63 PMID: 4794880
Electrophysiological analysis of the vestibulospinal reflex pathway of rabbit. I. Classification of tract cells.
Exp Brain Res. 1973 Jul 30;17(5):477-96 PMID: 4741250
Inferior olive: its role in motor learing.
Science. 1975 Dec 19;190(4220):1230-1 PMID: 128123
Effects of 3-acetylpyridine on the central nervous system of the rat, as demonstrated by silver methods.
Brain Res. 1974 Sep 13;77(3):349-64 PMID: 4851791
The cerebellar-evoked monosynaptic inhibition of Deiters' neurones.
Experientia. 1964 Sep 15;20(9):515-6 PMID: 5856344

Article Info

Journal

Experimental brain research

Abbr.

Exp Brain Res

ISSN

0014-4819

DOI

10.1007/BF00238802

Published

1978-09-15

Pages

143-5

Language

English

Region

Germany

NLM ID

0043312

Subset

External Links

PubMed source DOI: 10.1007/BF00238802 View journal details

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Reduction of the cerebellar stimulus effect on rat Deiters neurons after chemical destruction of the inferior olive.

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