Determinants that increase the serum resistance of Escherichia coli.

Infection and immunity ·Vol. 29 ·No. 1 ·1980-07-00 ·Pages 278-80

Taylor PW, Robinson MK

Abstract

The rfb locus, determining biosynthesis of O8-specific lipopolysaccharide side chains, was transferred to a rough mutant of Escherichia coli; recombinants producing a complete lipopolysaccharide were more resistant to the complement-mediated bactericidal action of human serum than the rough recipient. Inheritance of the his-linked genes for K27 antigen production did not alter the response to serum. The serum resistance of strains carrying O8 side chains, but not of strains with incomplete lipopolysaccharides, was further increased by inheritance of plasmids R1 and NR1.20

MeSH Terms

Antigens, Bacterial Blood Bactericidal Activity Escherichia coli/genetics,immunology,physiology Lipopolysaccharides/physiology Plasmids Recombination, Genetic

Chemicals

Antigens, Bacterial Lipopolysaccharides

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Taylor P W

Robinson M K

References (15)

15 references, click to expand

[Studies on the immune bacteriolysis. XIV. Requirement of all nine components of complement for immune bacteriolysis].
Biken J. 1968 Sep;11(3):203-6 PMID: 4888628
The serum bactericidal reaction. IV. Phenotypic conversion of Escherichia coli from serum-resistance to serum-sensitivity by diphenylamine.
J Infect Dis. 1969 Oct;120(4):437-44 PMID: 4898784
Immunochemistry of R lipopolysaccharides of Escherichia coli. Different core regions in the lipopolysaccharides of O group 8.
Eur J Biochem. 1969 Oct;10(3):501-10 PMID: 4899925
Biochemistry of the K antigens of Escherichia coli. Formation of the nucleoside diphosphate sugar precursors of the K27 antigen of E. coli 08:K27(A):H-.
Eur J Biochem. 1969 Dec;11(2):376-85 PMID: 4902611
The sensitivity to complement of strains of Escherichia coli related to their K antigens.
Immunology. 1970 Mar;18(3):331-46 PMID: 4986073
[Conjugation in E. coli O8:K27(A): H minus].
Zentralbl Bakteriol Orig. 1969;211(3):335-44 PMID: 4916843
Immunochemical studies on core lipopolysaccharides of Enterobacteriaceae of different genera.
Eur J Biochem. 1970 Jun;14(2):357-66 PMID: 4918557
The O8 antigen of Escherichia coli. Structure of the polysaccharide chain.
Eur J Biochem. 1972 Dec 4;31(2):320-8 PMID: 4119075
Genetical studies of serum resistance in Escherichia coli.
J Gen Microbiol. 1975 Jul;89(1):57-66 PMID: 1097595
Plasmid-mediated resistance to the bactericidal effects of normal rabbit serum.
Infect Immun. 1976 Sep;14(3):848-50 PMID: 786896
A protein factor associated with serum resistance in Escherichia coli.
J Med Microbiol. 1977 May;10(2):225-32 PMID: 323489
Genetic determinants of the synthesis of the polysaccharide capsular antigen K27(A) of Escherichia coli.
J Gen Microbiol. 1977 Jun;100(2):355-61 PMID: 330813
Effect of some R factors on the sensitivity of rough Enterobacteriaceae to human serum.
Infect Immun. 1977 Nov;18(2):278-82 PMID: 336539
Plasmid carriage and the serum sensitivity of enterobacteria.
Infect Immun. 1978 Oct;22(1):10-7 PMID: 365738
Cloned fragments of the plasmid ColV,I-K94 specifying virulence and serum resistance.
Nature. 1979 Jun 28;279(5716):778-81 PMID: 377103

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.29.1.278-280.1980

Published

1980-07-00

Pages

278-80

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC551108

Subset

External Links

PubMed source DOI: 10.1128/iai.29.1.278-280.1980 PMC Full Text View journal details

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Determinants that increase the serum resistance of Escherichia coli.

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