Changes in O6-methylguanine disappearance from rat liver DNA during chronic dimethylnitrosamine administration. A possible similarity between the system removing O6-methylguanine from DNA in rat liver and in Escherichia coli adapted to N-methyl-N'-nitro-N-nitrosoguanidine.

Animals DNA/metabolism DNA, Bacterial/metabolism Dimethylnitrosamine/pharmacology Enzyme Induction/drug effects Escherichia coli/drug effects,metabolism Female Guanine/analogs & derivatives,metabolism Liver/drug effects,metabolism Methylnitronitrosoguanidine/pharmacology Rats Time Factors

DNA, Bacterial Methylnitronitrosoguanidine Guanine DNA O-(6)-methylguanine Dimethylnitrosamine