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PMID: 6987539 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae.

Nature ·Vol. 284 ·No. 5755 ·1980-04-03 ·Pages 426-30

Szostak JW, Wu R

Abstract

Unequal sister chromatid exchanges occur at the ribosomal DNA locus of yeast during mitotic growth. The frequency of unequal crossing over, as measured by the deletion or duplication of an inserted genetic marker (LEU2), is sufficient to maintain the sequence homogeneity of the rDNA repeat units.

MeSH Terms
Chromosome Deletion Crossing Over, Genetic DNA Replication DNA, Fungal/genetics Genes Genetic Linkage Leucine/genetics Mitosis Plasmids RNA, Ribosomal/genetics Saccharomyces cerevisiae/genetics Sister Chromatid Exchange
Chemicals
DNA, Fungal RNA, Ribosomal Leucine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Szostak J W
Wu R
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
Published
1980-04-03
Pages
426-30
Language
English
Region
England
NLM ID
0410462
Subset
IM
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