The mechanism of cell-mediated cytotoxicity. I. Killing by murine cytotoxic T lymphocytes requires cell surface thiols and activated proteases.

Animals Cell Membrane/immunology Cytotoxicity, Immunologic Diamide/pharmacology Glutathione/analogs & derivatives,pharmacology Iodoacetamide/pharmacology Macromolecular Substances Mice Mice, Inbred BALB C Mice, Inbred CBA Mice, Inbred DBA Peptide Hydrolases/pharmacology Sulfhydryl Compounds/pharmacology T-Lymphocytes/immunology Tosylarginine Methyl Ester/pharmacology Tosyllysine Chloromethyl Ketone/pharmacology Tosylphenylalanyl Chloromethyl Ketone/pharmacology Trypsin Inhibitors/pharmacology

Macromolecular Substances Sulfhydryl Compounds Trypsin Inhibitors Diamide Tosyllysine Chloromethyl Ketone Tosylphenylalanyl Chloromethyl Ketone Tosylarginine Methyl Ester Peptide Hydrolases Glutathione Iodoacetamide