Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha.

Nature ·Vol. 275 ·No. 5679 ·1978-10-05 ·Pages 458-60

Ikegami S, Taguchi T, Ohashi M, Oguro M, Nagano H, Mano Y

Abstract

暂无摘要

MeSH Terms

Cell Division/drug effects DNA Replication/drug effects Diterpenes/pharmacology Meiosis/drug effects Mitosis/drug effects Nucleic Acid Synthesis Inhibitors Protein Biosynthesis/drug effects Sea Urchins/drug effects,metabolism Species Specificity Starfish/drug effects

Chemicals

Diterpenes Nucleic Acid Synthesis Inhibitors

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Ikegami S

Taguchi T

Ohashi M

Oguro M

Nagano H

Mano Y

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/275458a0

Published

1978-10-05

Pages

458-60

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/275458a0 View journal details

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Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha.

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