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PMID: 692721 Published · ppublish English Journal Article

Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA.

Nature ·Vol. 275 ·No. 5679 ·1978-10-05 ·Pages 416-20

Laskey RA, Honda BM, Mills AD, Finch JT

Abstract

The nucleosome subunits of chromatin are assembled from histones and DNA by an acidic protein which binds histones. The nucleosome assembly protein has been identified and purified from eggs of Xenopus laevis.

MeSH Terms
Animals Chromatin/ultrastructure DNA/metabolism Female Histones/metabolism Hot Temperature Isoelectric Point Molecular Weight Oocytes/physiology Osmolar Concentration Proteins/metabolism Xenopus
Chemicals
Chromatin Histones Proteins DNA
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Laskey R A
Honda B M
Mills A D
Finch J T
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/275416a0
Published
1978-10-05
Pages
416-20
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/275416a0 View journal details
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