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PMID: 6912819 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Properdin factor B polymorphism in continental Italy and Sardinia.

Human genetics ·Vol. 58 ·No. 2 ·1981-00-00 ·Pages 209-12

Malavasi F, Olivetti E, Milanese C, Carbonara AO

Abstract

A sample of healthy unrelated individuals (882 from Continental Italy and Sicily, and 139 from Sardinia) were typed for HLA and Bf polymorphisms. Bf gene frequencies in Continental Italy and Sicily show an intermediate position among European populations, with Lapps on one side and Basques on the other side; while a very peculiar pattern is observed among Sardinians, with an impressive similarity with French Basques and with the highest F1 gene frequency so far observed. The HLA:Bf gametic associations in Italy and Sardinia are also reported, which confirm the different ethnic background of these populations.

MeSH Terms
Complement Factor B/genetics Enzyme Precursors/genetics Ethnicity Europe Gene Frequency Genetic Linkage HLA Antigens/genetics Humans Italy Polymorphism, Genetic
Chemicals
Enzyme Precursors HLA Antigens Complement Factor B
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Malavasi F
Olivetti E
Milanese C
Carbonara A O
References (21)
21 references, click to expand
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Article Info
Journal
Human genetics
Abbr.
Hum Genet
ISSN
0340-6717
DOI
10.1007/BF00278713
Published
1981-00-00
Pages
209-12
Language
English
Region
Germany
NLM ID
7613873
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00278713 View journal details
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