Cyclophosphamide effects on murine cryptococcosis.

Infection and immunity ·Vol. 21 ·No. 2 ·1978-08-00 ·Pages 674-7

Graybill JR, Mitchell L

Abstract

BALB/c mice were given cyclophosphamide and challenged with Cryptococcus neoformans. Delayed-type hypersensitivity was transiently depressed, and survival was either unaffected or shortened by cyclophosphamide.

MeSH Terms

Animals Cryptococcosis/immunology,mortality Cyclophosphamide/pharmacology Hypersensitivity, Delayed/immunology Male Mice Mice, Inbred BALB C

Chemicals

Cyclophosphamide

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Graybill J R

Mitchell L

References (9)

9 references, click to expand

Host defense in cryptococcosis. I. An in vivo model for evaluating immune response.
Int Arch Allergy Appl Immunol. 1978;57(2):101-13 PMID: 346496
Influence of cyclophosphamide on delayed hypersensitivity and acquired cellular resistance to Listeria monocytogenes in the mouse.
Immunology. 1977 Jun;32(6):1027-32 PMID: 885586
Cyclophosphamide pretreatment and protection against malaria.
Infect Immun. 1976 Oct;14(4):1103-5 PMID: 791863
Effects of BCG, Corynebacterium parvum, and methanol-extration residue in the reduction of mortality from Staphylococcus aureus and Candida albicans infections in immunosuppressed mice.
Infect Immun. 1975 Dec;12(6):1325-30 PMID: 1107224
The role of the classical and alternate complement pathways in host defenses against Cryptococcus neoformans infection.
J Immunol. 1974 Jun;112(6):2260-70 PMID: 4596700
Potentiation of T-cell-mediated immunity by selective suppression of antibody formation with cyclophosphamide.
J Exp Med. 1974 Jun 1;139(6):1529-39 PMID: 4598017
Participation of cyclophosphamide-sensitive T cells in graft-vs-host reactions.
J Immunol. 1976 Sep;117(3):871-5 PMID: 8571
Effect of cyclophosphamide on Histoplasma capsulatum infections in mice.
Infect Immun. 1974 Feb;9(2):261-5 PMID: 4816459
Cyclophosphamide suppression of established cell-mediated immunity. Quantitative vs. qualitative changes in lymphocyte populations.
J Clin Invest. 1975 Jul;56(1):65-70 PMID: 1095612

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.21.2.674-677.1978

Published

1978-08-00

Pages

674-7

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC422048

Subset

External Links

PubMed source DOI: 10.1128/iai.21.2.674-677.1978 PMC Full Text View journal details

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Cyclophosphamide effects on murine cryptococcosis.

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