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PMID: 6885047 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Linkage relationships between Retinoschisis, Xg, and a cloned DNA sequence from the distal short arm of the X chromosome.

Human genetics ·Vol. 64 ·No. 2 ·1983-00-00 ·Pages 143-5

Wieacker P, Wienker TF, Dallapiccola B, Bender K, Davies KE, Ropers HH

Abstract

A cloned DNA sequence, RC8, from the short arm of the X chromosome which is linked to the Duchenne muscular dystrophy (DMD) gene has been employed to study linkage relationships with the Xg-linked retinoschisis (RS) locus. Results of three point linkage analyses in two families suggest that the gene order on Xp is Xg-RS-RC8. Moreover, it can be inferred from these date that the genetic distance between Xg and DMD is approximately 55 cM.

MeSH Terms
Alleles Cloning, Molecular Crossing Over, Genetic DNA/genetics Female Genetic Linkage Humans Male Pedigree Phenotype Retinal Diseases/genetics Sex Chromosome Aberrations/genetics X Chromosome/ultrastructure
Chemicals
DNA
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Wieacker P
Wienker T F
Dallapiccola B
Bender K
Davies K E
Ropers H H
References (11)
11 references, click to expand
  1. Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
    Am J Hum Genet. 1980 May;32(3):314-31 PMID: 6247908
  2. Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.
    Am J Hum Genet. 1974 Sep;26(5):588-97 PMID: 4422075
  3. Cloning of a representative genomic library of the human X chromosome after sorting by flow cytometry.
    Nature. 1981 Oct 1;293(5831):374-6 PMID: 6456416
  4. Linkage studies in a family with X-linked recessive ichthyosis employing a cloned DNA sequence from the distal short arm of the X chromosome.
    Hum Genet. 1983;63(2):113-6 PMID: 6301973
  5. Evolution of sickle variant gene.
    Lancet. 1979 Apr 28;1(8122):923 PMID: 86686
  6. Linkage relationship of a cloned DNA sequence on the short arm of the X chromosome to Duchenne muscular dystrophy.
    Nature. 1982 Nov 4;300(5887):69-71 PMID: 6982420
  7. Linkage analysis of two cloned DNA sequences flanking the Duchenne muscular dystrophy locus on the short arm of the human X chromosome.
    Nucleic Acids Res. 1983 Apr 25;11(8):2303-12 PMID: 6304647
  8. Steroid sulfatase activity in cultured fibroblasts of XX males.
    Cytogenet Cell Genet. 1981;30(3):168-73 PMID: 6945932
  9. Assignment by deletion mapping of the steroid sulfatase X-linked ichthyosis locus to Xp223.
    Hum Genet. 1980;54(2):205-6 PMID: 6930361
  10. Hereditary retinoschisis.
    Am J Ophthalmol. 1961 Jun;51:1193-200 PMID: 13705184
  11. [Diagnostic error in X-chromosomal hereditary retinoschisis].
    Buch Augenarzt. 1978;73:139-42 PMID: 568984
Article Info
Journal
Human genetics
Abbr.
Hum Genet
ISSN
0340-6717
DOI
10.1007/BF00327111
Published
1983-00-00
Pages
143-5
Language
English
Region
Germany
NLM ID
7613873
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00327111 View journal details
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