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PMID: 6853348 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Light microscopic, histochemical and ultrastructural studies of human lymph node paracortical venules.

Journal of anatomy ·Vol. 136 ·No. Pt 2 ·1983-03-00 ·Pages 349-62

Freemont AJ, Jones CJ

Abstract

The light microscopic, histochemical and electron microscopic appearances of human lymph node paracortical high endothelial venules are described, and indicate that the vessels are metabolically active and involved in secretion. A comparison is drawn between these vessels and the majority of lymph node vessels lined by flat endothelium. The evidence suggests that these vessels are identical to similar vessels in the lymph nodes of experimental animals and which are known to be the site of selective migration of lymphocytes into lymph nodes. The correlation between the structural and cytochemical findings and their probable function is discussed.

MeSH Terms
Alkaline Phosphatase/analysis Basement Membrane/ultrastructure Carboxylesterase Carboxylic Ester Hydrolases/analysis Endothelium/ultrastructure Glucuronidase/analysis Histocytochemistry Humans Lymph Nodes/enzymology,ultrastructure Lymphocytes/ultrastructure Microscopy, Electron
Chemicals
Carboxylic Ester Hydrolases Carboxylesterase Alkaline Phosphatase Glucuronidase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Freemont A J
Jones C J
References (27)
27 references, click to expand
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Article Info
Journal
Journal of anatomy
Abbr.
J Anat
ISSN
0021-8782
Published
1983-03-00
Pages
349-62
Language
English
Region
England
NLM ID
0137162
PMCID
PMC1170980
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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