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PMID: 6846964 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

DNA distribution and chromosome number in human cervical carcinoma.

Analytical and quantitative cytology ·Vol. 5 ·No. 1 ·1983-03-00 ·Pages 13-8

Jakobsen A, Nielsen KV, Rønne M

Abstract

The degree of ploidy of 15 human cervical carcinomas was investigated by use of flow cytometry and cytogenetic analysis. All tumors contained aneuploid cell populations. The results showed no correlation between ploidy and the clinical stage of the tumor. A high correlation was found between modal DNA content and modal chromosome number of the aneuploid cell populations, and it is concluded that flow cytometric analyses reflect the occurrence of tumor stemlines.

MeSH Terms

Aneuploidy Cell Cycle Chromosome Aberrations DNA, Neoplasm/analysis Female Flow Cytometry Humans Ploidies Uterine Cervical Neoplasms/analysis,genetics,pathology

Chemicals

DNA, Neoplasm

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Jakobsen A

Nielsen K V

Rønne M

Article Info

Journal

Analytical and quantitative cytology

Abbr.

Anal Quant Cytol

ISSN

0190-0471

Published

1983-03-00

Pages

13-8

Language

English

Region

United States

NLM ID

7911206

Subset

External Links

PubMed source

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DNA distribution and chromosome number in human cervical carcinoma.

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