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PMID: 6807316
Published · ppublish
English
Journal Article
Research Support, U.S. Gov't, P.H.S.
Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.
Abstract
暂无摘要
MeSH Terms
Adenosylmethionine Decarboxylase/metabolism
Animals
Carboxy-Lyases/antagonists & inhibitors
Drug Antagonism
Eflornithine
Kinetics
Mice
Neoplasms, Experimental/enzymology
Ornithine/analogs & derivatives,pharmacology
Ornithine Decarboxylase Inhibitors
Phorbols/pharmacology
Polyamines/biosynthesis
Putrescine/biosynthesis
Skin/drug effects,metabolism
Skin Neoplasms/chemically induced,enzymology
Spermidine/biosynthesis
Spermine/biosynthesis
Tetradecanoylphorbol Acetate/pharmacology
Chemicals
Ornithine Decarboxylase Inhibitors
Phorbols
Polyamines
Spermine
Ornithine
Carboxy-Lyases
Adenosylmethionine Decarboxylase
Tetradecanoylphorbol Acetate
Spermidine
Putrescine
Eflornithine
Article Info
Journal
Biochemical and biophysical research communications
Abbr.
Biochem Biophys Res Commun
ISSN
0006-291X
Published
1982-04-14
Pages
969-76
Language
English
Region
United States
NLM ID
0372516
Subset
IM
Grants
NCI NIH HHS · CA-07175 · United States
NCI NIH HHS · CA-22484 · United States
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