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PMID: 6805820 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

ABO blood group, secretor state, and susceptibility to recurrent urinary tract infection in women.

British medical journal (Clinical research ed.) ·Vol. 285 ·No. 6334 ·1982-07-03 ·Pages 7-9

Kinane DF, Blackwell CC, Brettle RP, Weir DM, Winstanley FP, Elton RA

Abstract

ABO blood group and secretor state was determined in 319 women with recurrent urinary tract infection and compared with those of a control group of 334 women of similar age ranges. Women of blood groups B and AB who are non-secretors of blood group substances showed a significant relative risk of recurrent urinary tract infection of 3.12 (95% confidence limits, 1.49 and 6.52) in comparison with other types. This appears to be a genuine example of synergy in which absence of anti-B isohaemagglutinin and secretor substances combines to give an increased risk of recurrent urinary tract infection. Determination of blood group and secretor state may provide additional information in identifying those at risk.

MeSH Terms
ABO Blood-Group System Adolescent Adult Aged Child Disease Susceptibility Female Humans Immunoglobulin A/analysis Immunoglobulin A, Secretory/analysis Middle Aged Recurrence Saliva/immunology Urinary Tract Infections/blood,immunology
Chemicals
ABO Blood-Group System Immunoglobulin A Immunoglobulin A, Secretory
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Kinane D F
Blackwell C C
Brettle R P
Weir D M
Winstanley F P
Elton R A
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20 references, click to expand
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Article Info
Journal
British medical journal (Clinical research ed.)
Abbr.
Br Med J (Clin Res Ed)
ISSN
0267-0623
Published
1982-07-03
Pages
7-9
Language
English
Region
England
NLM ID
8302911
PMCID
PMC1499148
Subset
IM
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