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PMID: 6802132 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Terminal synthesis of xanthommatin in Drosophila melanogaster. IV. Enzymatic and nonenzymatic catalysis.

Biochemical genetics ·Vol. 19 ·No. 11-12 ·1981-12-00 ·Pages 1211-21

Wiley K, Forrest HS

Abstract

Nonenzymatic and enzymatic catalysis of the oxidation of 3-hydroxykynurenine (and 3-hydroxyanthranilic acid) has been studied and characterized in Drosophila extracts, clearing up some of the confusion surrounding the synthesis of the brown eye pigment, xanthommatin. The genetic basis of the terminal steps in pigment synthesis remains obscure, since all mutants tested have full synthetase activity.

MeSH Terms
Amino Acids/biosynthesis Animals Cyanides/pharmacology Drosophila melanogaster/enzymology,metabolism Hot Temperature Oxazines/biosynthesis Oxidoreductases/metabolism Pigments, Biological/biosynthesis Xanthenes
Chemicals
Amino Acids Cyanides Oxazines Pigments, Biological Xanthenes xanthommatin Oxidoreductases 2-aminophenol oxidase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Wiley K
Forrest H S
References (9)
9 references, click to expand
  1. Transport defects as the physiological basis for eye color mutants of Drosophila melanogaster.
    Biochem Genet. 1975 Oct;13(9-10):603-13 PMID: 812484
  2. A mutation influencing the transportation of manganese, L-dopa, and L-tryptophan.
    Science. 1972 Apr 28;176(4033):410-2 PMID: 5026160
  3. Terminal synthesis of xanthommatin in Drosophila melanogaster. II. Enzymatic formation of the phenoxazinone nucleus.
    Biochem Genet. 1970 Aug;4(4):489-98 PMID: 4318521
  4. [On ommochromes. 20. On the distribution of ommatin in animals. New methods of identification and quantitative determination].
    Hoppe Seylers Z Physiol Chem. 1960;319:238-56 PMID: 13689419
  5. The ommochrome biosynthetic pathway in Drosophila melanogaster: the head particulate phenoxazinone synthase and the developmental onset of xanthommatin synthesis.
    Biochem Genet. 1976 Dec;14(11-12):1077-90 PMID: 828051
  6. Biosynthesis of the actinomycin chromophore; enzymatic conversion of 4-methyl-3-hydroxyanthranilic acid to actinocin.
    J Biol Chem. 1962 Mar;237:882-6 PMID: 14454375
  7. Terminal synthesis of xanthommatin in Drosophila melanogaster. 3. Mutational pleiotropy and pigment granule association of phenoxazinone synthetase.
    Genetics. 1973 Jan;73(1):45-56 PMID: 4631600
  8. ISOPHENOXAZINE SYNTHASE.
    Biochim Biophys Acta. 1964 Mar 9;81:507-16 PMID: 14170322
  9. The conversion of 3-hydroxyanthranilic acid to cinnabarinic acid by the nuclear fraction of rat liver.
    Biochem Biophys Res Commun. 1964 Jun 1;16(2):145-9 PMID: 5871803
Article Info
Journal
Biochemical genetics
Abbr.
Biochem Genet
ISSN
0006-2928
Published
1981-12-00
Pages
1211-21
Language
English
Region
United States
NLM ID
0126611
Subset
IM
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