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PMID: 6797957 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Mapping of the Fv-4 mouse gene controlling resistance to murine leukemia viruses.

International journal of cancer ·Vol. 28 ·No. 2 ·1981-08-15 ·Pages 237-40

Ikeda H, Sato H, Odaka T

Abstract

Fv-4, a gene controlling susceptibility to ecotropic murine leukemia viruses, was linked to both Pre-I (prealbumin) and Igh-I (immunoglobulin heavy-chain constant region) loci on chromosome 12 in mice. The gene order was Fv-4 - Pre-I - Igh-I, and the estimated frequency of recombination between Fv-4 and Pre-I was about 20%.

MeSH Terms

Animals Chromosome Mapping Crosses, Genetic Friend murine leukemia virus/immunology Genes, MHC Class II Genetic Markers H-2 Antigens/genetics Immunoglobulin Heavy Chains/genetics Leukemia, Experimental/immunology Mice Mice, Inbred Strains/genetics Prealbumin/genetics

Chemicals

Genetic Markers H-2 Antigens Immunoglobulin Heavy Chains Prealbumin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Ikeda H

Sato H

Odaka T

Article Info

Journal

International journal of cancer

Abbr.

Int J Cancer

ISSN

0020-7136

DOI

10.1002/ijc.2910280218

Published

1981-08-15

Pages

237-40

Language

English

Region

United States

NLM ID

0042124

Subset

External Links

PubMed source DOI: 10.1002/ijc.2910280218 View journal details

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Mapping of the Fv-4 mouse gene controlling resistance to murine leukemia viruses.

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