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PMID: 679261 Published · ppublish English Journal Article

Fine structure and composition of the submucous nerve plexus of the guinea-pig trachea.

Cell and tissue research ·Vol. 190 ·No. 2 ·1978-07-05 ·Pages 301-16

Hoyes AD, Barber P

Abstract

The ultrastructure of the nerves forming the submucous plexus of cervical and thoracic parts of the trachea was studied in the guinea-pig. Specimens were obtained from 6 animals perfused with warm fixative and from 6 animals in which pieces of trachea were incubated in buffer containing 5-hydroxydopamine before immersed in cold fixative. Of the two types of axonal terminal identified in the nerves, one contained mainly large dense-cored vesicles, and the second contained numerous small vesicles. In specimens incubated in 5-hydroxydopamine, the small vesicles of the latter terminals exhibited the electron-dense cores which are characteristic of adrenergic axonal terminals. Counts made on perfused specimens showed that, in both the thoracic and cervical parts of the trachea, the density of adrenergic terminals was higher than that of terminals containing mainly large dense-cored vesicles. Overall terminal density was, however, higher in the thoracic than in the cervical part of the trachea, and estimates of nerve size showed that this was associated with the presence in the thoracic plexus of a substantially greater proportion of nerves with less than 6 axons. The possible function of the nerves in the control of the calibre of the submucous blood vessels was discussed.

MeSH Terms
Animals Guinea Pigs Submucous Plexus/ultrastructure Trachea/innervation
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hoyes A D
Barber P
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51 references, click to expand
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Article Info
Journal
Cell and tissue research
Abbr.
Cell Tissue Res
ISSN
0302-766X
DOI
10.1007/BF00218177
Published
1978-07-05
Pages
301-16
Language
English
Region
Germany
NLM ID
0417625
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00218177 View journal details
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