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题目:: A monoclonal antibody that recognizes B cells and B cell precursors in mice.
作者:: Coffman(R L),Weissman(I L)
状态:: 发布时间1981-08-27 , 更新时间 2016-10-19
期刊:: J Exp Med
摘要:: The monoclonal antibody, RA3-2C2, appears to be specific for cells within the B cell lineage. This antibody does not recognize thymocytes, peripheral T cells, or nonlymphoid hematopoietic cells in the spleen or bone marrow. Nor does it recognize the pluripotent hematopoietic stem cells, the spleen colony-forming unit, All sIg+ B cells and most plasma cells are RA3-2C2+. In addition, approximately 20% of nucleated bone marrow cells are RA3-2C2+ but sIg-. This population contains B cell precursors that can give rise to sIg+ cells within 2 d in vitro.
语言:: eng
DOI:

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