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PMID: 6733565 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents.

Cancer investigation ·Vol. 2 ·No. 3 ·1984-00-00 ·Pages 223-31

Pegg AE

Abstract

暂无摘要

MeSH Terms
Alkylating Agents/toxicity Animals Carcinogens Cell Transformation, Neoplastic DNA/metabolism Guanine/analogs & derivatives,analysis Humans Liver/metabolism Methylation Methyltransferases/metabolism Neoplasms/chemically induced O(6)-Methylguanine-DNA Methyltransferase Pyrimidines/analysis Structure-Activity Relationship
Chemicals
Alkylating Agents Carcinogens Pyrimidines Guanine DNA O-(6)-methylguanine Methyltransferases O(6)-Methylguanine-DNA Methyltransferase
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Pegg A E
Article Info
Journal
Cancer investigation
Abbr.
Cancer Invest
ISSN
0735-7907
DOI
10.3109/07357908409104376
Published
1984-00-00
Pages
223-31
Language
English
Region
England
NLM ID
8307154
Subset
IM
Grants
NCI NIH HHS · 1 P30 CA-18450 · United States
NCI NIH HHS · CA-18137 · United States
External Links
PubMed source DOI: 10.3109/07357908409104376 View journal details
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