Home LiteratureArticle Details
PMID: 672955 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

The natural ovalbumin gene contains seven intervening sequences.

Nature ·Vol. 274 ·No. 5669 ·1978-07-27 ·Pages 328-33

Dugaiczyk A, Woo SL, Lai EC, Mace ML, McReynolds L, O'Malley BW

Abstract

EcoRI fragments of the natural ovalbumin gene were cloned and studied by hybridisation with mature ovalbumin mRNA, electron microscopy, restriction enzyme mapping and limited sequence analysis. The structural gene sequences coding for ovalbumin were found to be separated into eight sequentially orientated pieces by seven intervening sequences of various lengths.

MeSH Terms
Animals Base Sequence Chickens DNA Restriction Enzymes DNA, Recombinant Genes Microscopy, Electron Molecular Weight Nucleic Acid Hybridization Nucleic Acid Precursors/genetics Ovalbumin/genetics Plasmids RNA, Messenger/genetics
Chemicals
DNA, Recombinant Nucleic Acid Precursors RNA, Messenger Ovalbumin DNA Restriction Enzymes
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Dugaiczyk A
Woo S L
Lai E C
Mace M L
McReynolds L
O'Malley B W
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/274328a0
Published
1978-07-27
Pages
328-33
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/274328a0 View journal details
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