The elimination of 1,5-anhydroglucitol administered to rats.

Experientia ·Vol. 40 ·No. 5 ·1984-05-15 ·Pages 463-5

Pitkänen E, Pitkänen O

Abstract

Rat serum contains natural 1,5-anhydroglucitol. Injected or orally administered 1,5-anhydroglucitol was efficiently reabsorbed by the renal tubuli via a mechanism which had a saturation point at high serum 1,5- anhydroglucitol levels. The compound had a slow turnover rate in the body; its half-life is approximately 3 days. The compound was readily absorbed in the gut when administered orally.

MeSH Terms

Animals Deoxy Sugars/metabolism Deoxyglucose/blood,metabolism,urine Metabolic Clearance Rate Rats

Chemicals

Deoxy Sugars 1,5-anhydroglucitol Deoxyglucose

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Pitkänen E

Pitkänen O

References (5)

5 references, click to expand

Gas-chromatographic determination of polyol profiles in cerebrospinal fluid.
Clin Chem. 1978 Apr;24(4):545-8 PMID: 639257
Variation in polyol levels in cerebrospinal fluid and serum in diabetic patients.
Diabetologia. 1975 Dec;11(6):575-80 PMID: 1205026
Occurrence of I,5-anhydroglucitol in human cerebrospinal fluid.
Clin Chim Acta. 1973 Oct 12;48(2):159-66 PMID: 4758880
Serum 1,5-anhydroglucitol in normal subjects and in patients with insulin-dependent diabetes mellitus.
Scand J Clin Lab Invest. 1982 Sep;42(5):445-8 PMID: 6760372
Feeding and hyperglycemia induced by 1,5-anhydroglucitol in the rat.
Physiol Behav. 1981 Sep;27(3):401-5 PMID: 7335780

Article Info

Journal

Experientia

Abbr.

Experientia

ISSN

0014-4754

DOI

10.1007/BF01952387

Published

1984-05-15

Pages

463-5

Language

English

Region

Switzerland

NLM ID

0376547

Subset

External Links

PubMed source DOI: 10.1007/BF01952387

Analysis Services

The elimination of 1,5-anhydroglucitol administered to rats.

Contact

WeChat Official Account