Home LiteratureArticle Details
PMID: 670148 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Presence of squalene in gram-positive bacteria.

Journal of bacteriology ·Vol. 135 ·No. 1 ·1978-07-00 ·Pages 161-3

Amdur BH, Szabo EI, Socransky SS

Abstract

The presence of the isoprenoid squalene, synthesized de novo, was demonstrated in 64 out of 73 strains of gram-positive bacteria by thin-layer chromatography. This observation was confirmed by gas-liquid chromatography, chemical reactivity, incorporation of radiolabeled precursor, and by gas chromatography mass spectroscopy of thin-layer chromatography-recovered material.

MeSH Terms
Bacteria/analysis,metabolism Chromatography, Thin Layer Humans Mevalonic Acid/metabolism Mouth/microbiology Species Specificity Squalene/analysis,biosynthesis
Chemicals
Squalene Mevalonic Acid
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Amdur B H
Szabo E I
Socransky S S
References (7)
7 references, click to expand
  1. SEPARATION OF GLYCOSYL DIGLYCERIDES FROM PHOSPHATIDES USING SILICIC ACID COLUMN CHROMATOGRAPHY.
    J Lipid Res. 1965 Jan;6:3-6 PMID: 14280471
  2. On the origin of unsaturated fatty acids in clostridia.
    J Biol Chem. 1961 Oct;236:2596-601 PMID: 13899759
  3. Isolation of polyisoprenyl alcohols from Streptococcus faecalis.
    J Bacteriol. 1972 Dec;112(3):1302-5 PMID: 4344921
  4. Identification of fatty acids and aliphatic hydrocarbons in Sarcina lutea by gas chromatography and combined gas chromatography-mass spectrometry.
    J Bacteriol. 1967 Aug;94(2):333-43 PMID: 6039356
  5. Occurrence of squalene, di- and tetrahydrosqualenes, and vitamin MK8 in an extremely halophilic bacterium, Halobacterium cutirubrun.
    J Lipid Res. 1969 May;10(3):294-303 PMID: 5785002
  6. Separation of gangliosides, corticosteroids and water-soluble non-lipids from lipid extracts by sephadex columns.
    J Chromatogr. 1970 Feb 18;47(1):15-9 PMID: 5461460
  7. Occurrence of dehydrosqualene (C30 phytoene) in Staphylococcus aureus.
    Biochim Biophys Acta. 1968 Sep 2;164(1):88-93 PMID: 5680300
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.135.1.161-163.1978
Published
1978-07-00
Pages
161-3
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC224797
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.135.1.161-163.1978 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2