Inhibitory effects on lipid metabolism in cultured cells of ML-236B, a potent inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase.

Acetates/metabolism Cells, Cultured DNA/biosynthesis Fibroblasts/metabolism Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Kinetics L Cells/drug effects,metabolism Lipid Metabolism Lovastatin/analogs & derivatives Naphthalenes/pharmacology Oleic Acids/metabolism Protein Biosynthesis RNA/biosynthesis Skin/drug effects,metabolism

Acetates Hydroxymethylglutaryl-CoA Reductase Inhibitors Naphthalenes Oleic Acids mevastatin RNA DNA Lovastatin