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PMID: 6685521 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Plasma lipids in twins. Environmental and genetic influences.

Atherosclerosis ·Vol. 48 ·No. 3 ·1983-09-00 ·Pages 265-77

Whitfield JB, Martin NG

Abstract

A study on 205 pairs of male and females twins, aged from 18 to 34 years. showed significant heritabilities for total and high density lipoprotein cholesterol and for triglycerides. Significant effects of shared environment were also found for total and HDL cholesterol, possibly to a greater extent in women than in men. Triglycerides showed greater variance in men but a model specifying different sized environmental and genetic parameters in the two sexes gave a good fit and indicated that the factors influencing plasma triglycerides are the same in men and women although the effects they produce are scaled differently.

MeSH Terms
Adolescent Adult Cholesterol/blood Cholesterol, HDL Environment Female Genetic Variation Humans Lipids/blood Lipoproteins, HDL/blood Male Models, Genetic Pregnancy Registries Triglycerides/blood Twins
Chemicals
Cholesterol, HDL Lipids Lipoproteins, HDL Triglycerides Cholesterol
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Whitfield J B
Martin N G
Article Info
Journal
Atherosclerosis
Abbr.
Atherosclerosis
ISSN
0021-9150
Published
1983-09-00
Pages
265-77
Language
English
Region
Ireland
NLM ID
0242543
Subset
IM
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